| Title: | Blood concentrations of selected volatile organic compounds and neurobehavioral performance in a population-based sample |
| Author(s): | Wu T; Bhanegaonkar AJ; Flowers JW; |
| Address: | "Department of Public Health at East Tennessee State University, Johnson City 37614, USA. wut@etsu.edu" |
| Journal Title: | Arch Environ Occup Health |
| ISSN/ISBN: | 1933-8244 (Print) 1933-8244 (Linking) |
| Abstract: | "The authors analyzed data from a national sample to examine the relationships between blood concentrations of selected volatile organic compounds (VOCs) and the assessment scores of neurobehavioral evaluation tests. They calculated summary statistics to describe blood concentrations of 30 VOCs. For instance, the 95th percentiles were as follows: 1,1,1-trichloroethane, 0.799 microg/l; 1,4-dichlorobenzene, 11.081 microg/l; benzene, 0.476 microg/l; and toluene, 0.281 microg/l. For 1,4-dichlorobenzene, benzene, dibromochloromethane, and trichloroethene, a blood level higher than the 95th percentile was associated with a poorer neurobehavioral assessment score than was a blood level up to the 95th percentile. The authors found a linear relationship between blood toluene concentration and the Serial Digit Learning Test score. The findings suggest that exposure to certain VOCs may result in poor neurobehavioral performance. The study was exploratory and precludes a conclusive statement, so further investigation is warranted" |
| Keywords: | Adult Environmental Exposure Female Humans Male Middle Aged *Neuropsychological Tests Organic Chemicals/adverse effects/*blood United States Volatilization; |
| Notes: | "MedlineWu, Tiejian Bhanegaonkar, Abhijeet J Flowers, Joanne W eng Research Support, Non-U.S. Gov't 2007/05/17 Arch Environ Occup Health. 2006 Jan-Feb; 61(1):17-25. doi: 10.3200/AEOH.61.1.17-25" |
