| Title: | "A comparison of volatile fractions obtained from Lonicera macranthoides via different extraction processes: ultrasound, microwave, Soxhlet extraction, hydrodistillation, and cold maceration" |
| Author(s): | Wu C; Wang F; Liu J; Zou Y; Chen X; |
| Address: | "College of Agronomy, Sichuan Agricultural University, Chengdu, China. Key Laboratory of Crop Ecophysiology and Farming System in Southwest China, Ministry of Agriculture, Sichuan Agricultural University, Chengdu, China. College of Pharmacy, Sichuan Agricultural University, Chengdu, China" |
| DOI: | 10.1016/j.imr.2015.06.001 |
| ISSN/ISBN: | 2213-4220 (Print) 2213-4239 (Electronic) 2213-4220 (Linking) |
| Abstract: | "BACKGROUND: Hydrodistillation has been traditionally used to extract volatile fraction in traditional Chinese medicine. However, with the development of Soxhlet extraction (SE), microwave (MW), ultrasound (US), and cold maceration (CM), hydrodistillation (HD) is being replaced to meet some practical requirements. In this study, we investigated the effect of the five methods on the volatile fraction extract of Lonicera macranthoides. METHODS: Volatile fraction from the flower buds of Lonicera macranthoides was obtained by using different extraction methods, HD, SE, MW, US, and CM. The compositions of volatile fraction were analyzed by gas chromatography-mass spectrometric and further compared among extraction methods. RESULTS: Extracts obtained by the five methods reveal the qualitative and quantitative diversity in their compositions, especially for the low-content compositions. According to the results, SE shows the great value in the research where the high molecular-mass compound is of primary interest, and MW offers a way for the isolation of specific compound like octadecadienoic acid and hexadecanoic acid. HD, US, and CM have the advantage over SE and MW for the integrity of the constituents, whereas the phenomenon of compound degradation seems not so serious in solvent extraction methods such as US or CM as HD. Additionally, US and CM show superiority over time or material saving and diversity of the constituent. CONCLUSION: HD is still the best choice for the pure volatile fraction without organic solvent pollution. However, when it comes to some specifically actual demands, it can be replaced by the four methods for the volatile fraction extraction process, especially for production of certain compound groups" |
| Keywords: | Lonicera macranthoides extraction method hydrodistillation traditional Chinese medicine volatile fraction; |
| Notes: | "PubMed-not-MEDLINEWu, Chun Wang, Feng Liu, Jiang Zou, Yuanfeng Chen, Xingfu eng Netherlands 2015/09/01 Integr Med Res. 2015 Sep; 4(3):171-177. doi: 10.1016/j.imr.2015.06.001. Epub 2015 Jun 12" |
