| Title: | Common Strategies and Factors Affecting Off-Line Breath Sampling and Volatile Organic Compounds Analysis Using Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS) |
| Author(s): | Westphal K; Dudzik D; Waszczuk-Jankowska M; Graff B; Narkiewicz K; Markuszewski MJ; |
| Address: | "Department of Hypertension and Diabetology, Medical University of Gdansk, 80-214 Gdansk, Poland. Department of Biopharmaceutics and Pharmacodynamics, Faculty of Pharmacy, Medical University of Gdansk, 80-416 Gdansk, Poland" |
| ISSN/ISBN: | 2218-1989 (Print) 2218-1989 (Electronic) 2218-1989 (Linking) |
| Abstract: | "An analysis of exhaled breath enables specialists to noninvasively monitor biochemical processes and to determine any pathological state in the human body. Breath analysis holds the greatest potential to remold and personalize diagnostics; however, it requires a multidisciplinary approach and collaboration of many specialists. Despite the fact that breath is considered to be a less complex matrix than blood, it is not commonly used as a diagnostic and prognostic tool for early detection of disordered conditions due to its problematic sampling, analysis, and storage. This review is intended to determine, standardize, and marshal experimental strategies for successful, reliable, and especially, reproducible breath analysis" |
| Keywords: | breath sampling and analysis gas chromatography mass spectrometry metabolomics thermal desorption volatile organic compounds (VOC); |
| Notes: | "PubMed-not-MEDLINEWestphal, Kinga Dudzik, Danuta Waszczuk-Jankowska, Malgorzata Graff, Beata Narkiewicz, Krzysztof Markuszewski, Michal Jan eng UMO-2018/29/B/NZ5/02491/National Science Center/ Review Switzerland 2023/01/22 Metabolites. 2022 Dec 21; 13(1):8. doi: 10.3390/metabo13010008" |
