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Fly (Austin)

Title:		desat1: A Swiss army knife for pheromonal communication and reproduction?
Author(s):		Bousquet F; Ferveur JF;
Address:		"Centre des Sciences du Gout et de l'Alimentation, UMR CNRS, UMR INRA, Universite de Bourgogne, Dijon, France"
Journal Title:		Fly (Austin)
Year:		2012
Volume:		20120401
Issue:		2
Page Number:		102 - 107
DOI:		10.4161/fly.19554
ISSN/ISBN:		1933-6942 (Electronic) 1933-6934 (Linking)
Abstract:		The desat1 gene possesses an extraordinary-maybe unique-feature in the control of sensory communication systems: it codes for the two principal and complementary aspects-the emission and the reception-of Drosophila sex pheromones. These two complex aspects depend on separate genetic control indicating that desat1 pleiotropically acts on pheromonal communication. This gene also control other characters either related to reproduction and to osmoregulation. Such a functional pleiotropy may be related to the molecular structure of desat1 gene which combines a highly conserved coding region with fast evolving regulatory regions: It produces at least five transcripts all giving rise to the ?Os9-desaturase enzyme
Keywords:		"Alternative Splicing Animals Drosophila Proteins/*genetics Drosophila melanogaster/*physiology Fatty Acid Desaturases/*genetics Female *Genetic Pleiotropy Male Regulatory Sequences, Nucleic Acid Reproduction Sex Attractants/*physiology;"
Notes:		"MedlineBousquet, Francois Ferveur, Jean-Francois eng 2012/05/29 Fly (Austin). 2012 Apr-Jun; 6(2):102-7. doi: 10.4161/fly.19554. Epub 2012 Apr 1"