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J Breath Res

Title:		Chemical sensors for breath gas analysis: the latest developments at the Breath Analysis Summit 2013
Author(s):		Tisch U; Haick H;
Address:		"The Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion, Israel Institute of Technology, Haifa 3200003, Israel"
Journal Title:		J Breath Res
Year:		2014
Volume:		20140328
Issue:		2
Page Number:		27103 -
DOI:		10.1088/1752-7155/8/2/027103
ISSN/ISBN:		1752-7163 (Electronic) 1752-7155 (Linking)
Abstract:		"Profiling the body chemistry by means of volatile organic compounds (VOCs) in the breath opens exciting new avenues in medical diagnostics. Gas sensors could provide ideal platforms for realizing portable, hand-held breath testing devices in the near future. This review summarizes the latest developments and applications in the field of chemical sensors for diagnostic breath testing that were presented at the Breath Analysis Summit 2013 in Wallerfangen, Germany. Considerable progress has been made towards clinically applicable breath testing devices, especially by utilizing chemo-sensitive nanomaterials. Examples of several specialized breath testing applications are presented that are either based on stand-alone nanomaterial-based sensors being highly sensitive and specific to individual breath compounds over others, or on combinations of several highly specific sensors, or on experimental nanomaterial-based sensors arrays. Other interesting approaches include the adaption of a commercially available MOx-based sensor array to indirect breath testing applications, using a sample pre-concentration method, and the development of compact integrated GC-sensor systems. The recent trend towards device integration has led to the development of fully integrated prototypes of point-of-care devices. We describe and compare the performance of several prototypes that are based on different sensing technologies and evaluate their potential as low-cost and readily available next-generation medical devices"
Keywords:		"Breath Tests/*instrumentation/*methods Chromatography, Gas/instrumentation *Congresses as Topic Electronic Nose Gases/*analysis Germany Humans Nanostructures/chemistry;"
Notes:		"MedlineTisch, Ulrike Haick, Hossam eng Research Support, Non-U.S. Gov't Review England 2014/04/01 J Breath Res. 2014 Jun; 8(2):027103. doi: 10.1088/1752-7155/8/2/027103. Epub 2014 Mar 28"