| Title: | Identification of volatile basic components in tobacco by headspace liquid-phase microextraction coupled to matrix-assisted laser desorption/ionization with Fourier transform mass spectrometry |
| Author(s): | Sun S; Cheng Z; Xie J; Zhang J; Liao Y; Wang H; Guo Y; |
| Address: | "Shanghai Mass Spectrometry Center, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, Shanghai, 200032, China" |
| Journal Title: | Rapid Commun Mass Spectrom |
| ISSN/ISBN: | 0951-4198 (Print) 0951-4198 (Linking) |
| Abstract: | "A method incorporating headspace liquid-phase microextraction (HS-LPME) coupled to matrix-assisted laser desorption/ionization (MALDI) with Fourier transform mass spectrometry (FTMS) was established to analyze volatile basic components in tobacco. The sample preparation volume for MALDI-MS was compatible with the volume of the solvent microdrop in the HS-LPME procedure. The pH and the polarity of the solvent for HS-LPME were adjusted by choice of the MALDI matrix and matrix additive. Based on the elemental composition and tandem mass spectrometry information, 25 volatile nitrogenous compounds in tobacco were detected and identified. The approach is fast and sensitive, and has the potential for automation for high-throughput analysis. This approach offers an alternative method for analysis of trace volatile organic compounds in complex samples" |
| Keywords: | "Gas Chromatography-Mass Spectrometry/*methods Organic Chemicals/*analysis Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/*methods Spectroscopy, Fourier Transform Infrared/*methods Tobacco/*chemistry Volatilization;" |
| Notes: | "MedlineSun, Shihao Cheng, Zhihong Xie, Jianping Zhang, Jianxun Liao, Yuanxi Wang, Haoyang Guo, Yinlong eng Research Support, Non-U.S. Gov't England 2005/03/16 Rapid Commun Mass Spectrom. 2005; 19(8):1025-30. doi: 10.1002/rcm.1884" |
