| Title: | Mutagenicity of fecal extracts from carnivorous and herbivorous animals |
| Author(s): | Stich HF; Stich W; Acton AB; |
| DOI: | 10.1016/0165-1218(80)90089-0 |
| ISSN/ISBN: | 0027-5107 (Print) 0027-5107 (Linking) |
| Abstract: | "Extracts of the feces of 3 carnivorous animals (dog, river otter and sea gull) and 5 herbivorous animals (cow, horse, sheep, chicken and goose) induced chromosome aberrations (breaks and exchanges) in cultured CHO cells. The addition of CuII (10(-4)M) enhanced the clastogenic effect of fecal extracts of the examined animals with the exceptiion of 1 dog and 3 cow samples. Catalase reduced the chromosome-breaking and mitosis-inhibiting capacities of fecal extracts. These results indicate the presence of hydrogen peroxide-forming compounds. The possibility must be considered that animal and human excreta may be a major source of mutagens entering man's environment" |
| Keywords: | Animals Birds/physiology Cattle Cell Line Chickens/physiology *Chromosome Aberrations Chromosomes/drug effects Cricetinae Cricetulus Feces/*analysis Female Geese/physiology Horses/physiology *Mutagens Otters/physiology Ovary Sheep/physiology; |
| Notes: | "MedlineStich, H F Stich, W Acton, A B eng Netherlands 1980/06/01 Mutat Res. 1980 Jun; 78(2):105-12. doi: 10.1016/0165-1218(80)90089-0" |
