| Title: | Equilibria of semi-volatile isothiazolinones between air and glass surfaces measured by gas chromatography and Raman spectroscopy |
| Author(s): | Sohn S; Huong VT; Nguyen PD; Ly NH; Jang S; Lee H; Lee C; Lee JI; Vasseghian Y; Joo SW; Zoh KD; |
| Address: | "Department of Environmental Health Sciences, School of Public Health, Seoul National University, Seoul 08826, Republic of Korea. Department of Chemistry, Soongsil University, Seoul, 06978, Republic of Korea. Department of Chemistry, Gachon University, Seongnam, 13120, Republic of Korea. Department of Chemistry, Sejong University, Seoul, 143-747, Republic of Korea. Department of Chemical & Biological Engineering, Seokyeong University, Seoul, 02713, Republic of Korea. Korea Testing & Research Institute, Gwacheon, 13810, Republic of Korea. Department of Chemistry, Soongsil University, Seoul, 06978, Republic of Korea; School of Engineering, Lebanese American University, Byblos, Lebanon; University Centre for Research & Development, Department of Mechanical Engineering, Chandigarh University, Gharuan, Mohali, Punjab, 140413, India; Department of Sustainable Engineering, Saveetha School of Engineering, SIMATS, Chennai, 602105, India. Electronic address: vasseghian@ssu.ac.kr. Department of Chemistry, Soongsil University, Seoul, 06978, Republic of Korea. Electronic address: sjoo@ssu.ac.kr. Department of Environmental Health Sciences, School of Public Health, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: zohkd@snu.ac.kr" |
| DOI: | 10.1016/j.envres.2022.114908 |
| ISSN/ISBN: | 1096-0953 (Electronic) 0013-9351 (Linking) |
| Abstract: | "Trace amounts of semi-volatile organic compounds (SVOCs) of the two isothiazolinones of 2-methylisothiazol-3(2H)-one (MIT) and 2-octyl-4-isothiazolin-3-one (OIT) were detected both in the air and on glass surfaces. Equilibria of SVOCs between air and glass were examined by solid phase microextraction-gas chromatography/mass spectrometry (SPME-GC/MS). Surface to air distribution ratios of K(sa) for MIT and OIT were determined to be 5.10 m and 281.74 m, respectively, suggesting more abundant MIT in the gas phase by a factor of approximately 55. In addition, a facile method of silver nanocube (AgNC)-assisted surface-enhanced Raman scattering (SERS) has been developed for the rapid and sensitive detection of MIT and OIT on glass surfaces. According to MIT and OIT concentration-correlated SERS intensities of Raman peaks at approximately 1585 cm(-1) and approximately 1125 cm(-1), respectively. Their calibration curves have been obtained in the concentration ranges between 10(-3) to 10(-10) M and 10(-3) to 10(-11) M with their linearity of 0.9986 and 0.9989 for MIT and OIT, respectively. The limits of detection (LODs) of the two isothiazolinones were estimated at 10(-10) M, and 10(-11) M for MIT and OIT, respectively. Our results indicate that AgNC-assisted SERS spectra are a rapid and high-ultrasensitive method for the quantification of MIT and OIT in practical applications. The development of analytical methods and determination of the Ksa value obtained in this study can be applied to the prediction of the exposure to MIT and OIT from various chemical products and dynamic behaviors to assess human health risks in indoor environments" |
| Keywords: | "Humans *Spectrum Analysis, Raman Gas Chromatography-Mass Spectrometry/methods Solid Phase Microextraction/methods *Volatile Organic Compounds/analysis Limit of Detection Isothiazolinone Silver nanocubes Surface-air equilibria Surface-enhanced Raman scatte;" |
| Notes: | "MedlineSohn, Seungwoon Huong, Vu Thi Nguyen, Phuong-Dong Ly, Nguyen Hoang Jang, Soonmin Lee, Hyewon Lee, Cheolmin Lee, Jung Il Vasseghian, Yasser Joo, Sang-Woo Zoh, Kyung-Duk eng Research Support, Non-U.S. Gov't Netherlands 2022/11/29 Environ Res. 2023 Feb 1; 218:114908. doi: 10.1016/j.envres.2022.114908. Epub 2022 Nov 26" |
