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Molecules

Title:		Multidisciplinary Studies of Folk Medicine 'Five Thieves' Oil' (Olejek Pieciu Zlodziei) Components
Author(s):		Siejak P; Smulek W; Fathordobady F; Grygier A; Baranowska HM; Rudzinska M; Masewicz L; Jarzebska M; Nowakowski PT; Makiej A; Kazemian P; Drobnik P; Stachowiak B; Jarzebski M; Pratap-Singh A;
Address:		"Department of Physics and Biophysics, Faculty of Food Science and Nutrition, Poznan University of Life Sciences, Wojska Polskiego 38/42, 60-637 Poznan, Poland. Institute of Chemical Technology and Engineering, Poznan University of Technology, Berdychowo 4, 60-637 Poznan, Poland. Food, Nutrition and Health, University of British Columbia, 2205, East Mall, Vancouver, BC V6T 1Z4, Canada. Department of Technology of Plant Origin Food, Faculty of Food Science and Nutrition, Poznan University of Life Sciences, ul. Wojska Polskiego 31, 60-624 Poznan, Poland. Poznan University of Life Sciences, 60-624 Poznan, Poland. Institute of Pedagogy, Rzeszow University, Jalowego 24, 35-010 Rzeszow, Poland. Department of Biology, Faculty of Sciences, University of British Columbia, 1103-6270 University Blvd, Biological Sciences Building, Vancouver, BC V6T 1Z4, Canada. Department of Orthopedics and Traumatology, Poznan University of Medical Sciences, 28 Czerwca 1956 135/147, 61-545 Poznan, Poland"
Journal Title:		Molecules
Year:		2021
Volume:		20210514
Issue:		10
Page Number:		-
DOI:		10.3390/molecules26102931
ISSN/ISBN:		1420-3049 (Electronic) 1420-3049 (Linking)
Abstract:		"To meet the growing interest in natural antibacterial agents, we evaluated the physicochemical and biological properties of the folk medicine known as 'five thieves' oil' (Polish name: olejek pieciu zlodziei). Five thieves' oil consists of a mixture of five oils: rosemary, lemon, clove, eucalyptus, and cinnamon. In this study, we performed gas chromatography, FTIR, and UV-vis spectroscopic analysis, as well as L-a-b color tests, contact angle determination, and surface tension determination. To verify its antibacterial activity, the metabolic activity and changes in cell membrane permeability of bacteria of the genus Pseudomonas were studied. As a result, it was found that among the constituent oils, the oils of clove and cinnamon were the least volatile and, at the same time, had the strongest antibacterial activity. However, a mix of all the oils also showed comparable activity, which was even more pronounced for the oils after 4 weeks of aging. This effect can be linked to the high content of terpene derivatives such as eugenol and cinnamaldehyde, which can cause changes in bacterial membrane permeability, affecting cell activity and survival. This study is the first to characterize the constituents of the popular folk medicine five thieves' oil, confirming and explaining its strong antibacterial activity, thus constituting a significant contribution to contemporary health education"
Keywords:		"Anti-Infective Agents/pharmacology Bacteria/cytology/drug effects/metabolism Cell Membrane Permeability/drug effects Magnetic Resonance Spectroscopy *Medicine, Traditional Microbial Sensitivity Tests Plant Oils/*chemistry Refractometry Spectrometry, Fluor;"
Notes:		"MedlineSiejak, Przemyslaw Smulek, Wojciech Fathordobady, Farahnaz Grygier, Anna Baranowska, Hanna Maria Rudzinska, Magdalena Masewicz, Lukasz Jarzebska, Malgorzata Nowakowski, Piotr T Makiej, Aleksandra Kazemian, Pardis Drobnik, Pawel Stachowiak, Barbara Jarzebski, Maciej Pratap-Singh, Anubhav eng Switzerland 2021/06/03 Molecules. 2021 May 14; 26(10):2931. doi: 10.3390/molecules26102931"