| Title: | Kisspeptin and the regulation of the reproductive axis in domestic animals |
| Author(s): | Scott CJ; Rose JL; Gunn AJ; McGrath BM; |
| Address: | "C Scott, School of Biomedical Sciences, Charles Sturt University - Wagga Wagga Campus, Wagga Wagga, Australia. J Rose, School of Biomedical Sciences, Charles Sturt University - Wagga Wagga Campus, Wagga Wagga, Australia. A Gunn, School of Animal and Veterinary Sciences, Charles Sturt University - Wagga Wagga Campus, Wagga Wagga, Australia. B McGrath, School of Biomedical Sciences, Charles Sturt University - Wagga Wagga Campus, Wagga Wagga, Australia" |
| ISSN/ISBN: | 1479-6805 (Electronic) 0022-0795 (Linking) |
| Abstract: | "The control of reproductive processes involves the integration of a number of factors from the internal and external environment, with the final output signal of these processes being the pulsatile secretion of gonadotrophin releasing hormone (GnRH) from the hypothalamus. These factors include the feedback actions of sex steroids, feed intake and nutritional status, season/photoperiod, pheromones, age and stress. Understanding these factors and how they influence GnRH secretion and hence reproduction is important for the management of farm animals. There is evidence that the RF-amide neuropeptide, kisspeptin, may be involved in relaying the effects of these factors to the GnRH neurons. This paper will review the evidence from the common domestic animals (sheep, goats, cattle, horses and pigs), that kisspeptin neurons are i) regulated by the factors listed above, ii) contact GnRH neurons, and iii) involved in the regulation of GnRH/gonadotrophin secretion" |
| Notes: | "PublisherScott, Christopher J Rose, Jessica L Gunn, Allan J McGrath, Briony M eng Review England 2018/11/08 J Endocrinol. 2018 Oct 1:JOE-18-0485.R1. doi: 10.1530/JOE-18-0485" |
