| Title: | Assessing Human Exposure to Organic Pollutants in the Indoor Environment |
| Author(s): | Salthammer T; Zhang Y; Mo J; Koch HM; Weschler CJ; |
| Address: | "Department of Material Analysis and Indoor Chemistry, Fraunhofer WKI, 38108, Braunschweig, Bienroder Weg 54E, Germany. Department of Building Science, Tsinghua University, Beijing Key Laboratory of Indoor Air Quality Evaluation and Control, Beijing, 100084, PR China. Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Institute of the Ruhr-University Bochum, 44789, Bochum, Burkle-de-la-Camp Platz 1, Germany. Environmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ, 08854, USA" |
| ISSN/ISBN: | 1521-3773 (Electronic) 1433-7851 (Linking) |
| Abstract: | "There is an ongoing probing of the role of chemicals in the indoor environment. The majority of potential target substances are so-called very volatile, volatile, and semi-volatile organic compounds (VVOCs, VOCs, and SVOCs). Depending on their physical properties and the mass transfer conditions, they are distributed in or between the gas phase, particle phase, settled house dust, surface films, clothing, and other fabrics as well as the exposed skin and hair of the occupants themselves. Therefore, inhalation, ingestion, and dermal uptake all must be considered as relevant pathways for exposure assessment in human habitats. Exposure to VVOCs, VOCs, and SVOCs can be estimated by measuring their concentrations in relevant indoor compartments or by determining the amounts of the target compounds and/or their metabolites in urine and blood. Assessing the various routes of exposure often requires a combination of sophisticated and interdisciplinary theoretical background and experimental techniques. Consequently, close communication and collaboration between chemical and exposure scientists are needed to achieve a better understanding of human exposure to chemical substances in various indoor environments. Embedded in the toxicological context, this is the basis for assessing the corresponding health risks and for determining control strategies or approaches to limit such risks" |
| Keywords: | "*Air Pollution, Indoor Carbon Monoxide/analysis Dust/analysis *Environmental Exposure Environmental Monitoring Gases/chemistry Humans Volatile Organic Compounds/*analysis/blood/urine analytical techniques gas/particle distribution human biomonitoring indo;" |
| Notes: | "MedlineSalthammer, Tunga Zhang, Yinping Mo, Jinhan Koch, Holger M Weschler, Charles J eng Research Support, Non-U.S. Gov't Review Germany 2018/03/15 Angew Chem Int Ed Engl. 2018 Sep 17; 57(38):12228-12263. doi: 10.1002/anie.201711023. Epub 2018 Aug 13" |
