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Autophagy

Title:		"Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile"
Author(s):		Rossiter H; Copic D; Direder M; Gruber F; Zoratto S; Marchetti-Deschmann M; Kremslehner C; Sochorova M; Nagelreiter IM; Mlitz V; Buchberger M; Lengauer B; Golabi B; Sukseree S; Mildner M; Eckhart L; Tschachler E;
Address:		"Department of Dermatology, Medical University of Vienna, Vienna, Austria. Laboratory for Cardiac and Thoracic Diagnosis, Regeneration and Applied Immunology, Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria. Institute of Chemical Technologies and Analytics, Technical University of Vienna, Vienna, Austria. Center for Brain Research, Department of Molecular Neurosciences, Medical University of Vienna, Vienna, Austria"
Journal Title:		Autophagy
Year:		2022
Volume:		20210907
Issue:		5
Page Number:		1005 - 1019
DOI:		10.1080/15548627.2021.1966716
ISSN/ISBN:		1554-8635 (Electronic) 1554-8627 (Print) 1554-8627 (Linking)
Abstract:		ATG7: autophagy related 7; BODIPY: boron dipyrromethene; DAG: diacyl glycerides; DBI: diazepam binding inhibitor; GFP: green fluorescent protein; KRT14: keratin 14; HPLC-MS: high performance liquid chromatography-mass spectrometry; LD: lipid droplet; MAP1LC3/LC3: microtubule-associated protein 1 light chain 3; MSI: mass spectrometric imaging; ORO: Oil Red O; PC: phosphatidylcholine; PE: phosphatidylethanolamine; PG: preputial gland; PLIN2: perilipin 2; PtdIns: phosphatidylinositol; PL: phospholipids; POPC: 1-palmitoyl-2-oleoyl-PC; PS: phosphatidylserine; qRT-PCR: quantitative reverse transcribed PCR; SG: sebaceous gland; scRNAseq: single-cell RNA sequencing; TAG: triacylglycerides; TLC: thin layer chromatography
Keywords:		"*Aging, Premature Animals Autophagy/genetics Mice Perilipin-2 Pheromones Phosphatidylserines Phospholipids *Sebum Autophagosomes Gfp-lc3 lipid droplets perilipin sebocytes;"
Notes:		"MedlineRossiter, Heidemarie Copic, Dragan Direder, Martin Gruber, Florian Zoratto, Samuele Marchetti-Deschmann, Martina Kremslehner, Christopher Sochorova, Michaela Nagelreiter, Ionela-Mariana Mlitz, Veronika Buchberger, Maria Lengauer, Barbara Golabi, Bahar Sukseree, Supawadee Mildner, Michael Eckhart, Leopold Tschachler, Erwin eng Research Support, Non-U.S. Gov't 2021/09/08 Autophagy. 2022 May; 18(5):1005-1019. doi: 10.1080/15548627.2021.1966716. Epub 2021 Sep 7"