| Title: | Differentiation between decomposed remains of human origin and bigger mammals |
| Author(s): | Rosier E; Loix S; Develter W; Van de Voorde W; Cuypers E; Tytgat J; |
| Address: | "Department of Pharmaceutical and Pharmacological Sciences, Toxicology and Pharmacology, University of Leuven (KU Leuven), Campus Gasthuisberg, O&N2, PO Box 922, Herestraat 49, 3000 Leuven, Belgium. Imaging & Pathology Department, Division Forensic Biomedical Sciences, University of Leuven (KU Leuven), Campus Sint-Rafael, Kapucijnenvoer 33, 3000 Leuven, Belgium. Department of Pharmaceutical and Pharmacological Sciences, Toxicology and Pharmacology, University of Leuven (KU Leuven), Campus Gasthuisberg, O&N2, PO Box 922, Herestraat 49, 3000 Leuven, Belgium. Electronic address: jan.tytgat@pharm.kuleuven.be" |
| DOI: | 10.1016/j.jflm.2017.06.003 |
| ISSN/ISBN: | 1878-7487 (Electronic) 1752-928X (Linking) |
| Abstract: | "This study is a follow-up study in the search for a human specific marker in the decomposition where the VOC-profile of decomposing human, pig, lamb and roe remains were analyzed using a thermal desorber combined with a gas chromatograph coupled to a mass spectrometer in a laboratory environment during 6 months. The combination of 8 previously identified human and pig specific compounds (ethyl propionate, propyl propionate, propyl butyrate, ethyl pentanoate, 3-methylthio-1-propanol, methyl(methylthio)ethyl disulfide, diethyl disulfide and pyridine) was also seen in these analyzed mammals. However, combined with 5 additional compounds (hexane, heptane, octane, N-(3-methylbutyl)- and N-(2-methylpropyl)acetamide) human remains could be separated from pig, lamb and roe remains. Based on a higher number of remains analyzed, as compared with the pilot study, it was no longer possible to rely on the 5 previously proposed esters to separate pig from human remains. From this follow-up study reported, it was found that pyridine is an interesting compound specific to human remains. Such a human specific marker can help in the training of cadaver dogs or in the development of devices to search for human remains. However, further investigations have to verify these results" |
| Keywords: | Animals Biomarkers/analysis *Body Remains Deer Forensic Pathology Gas Chromatography-Mass Spectrometry Humans *Postmortem Changes Principal Component Analysis Sheep Species Specificity Swine Volatile Organic Compounds/*analysis Decomposition Human specifi; |
| Notes: | "MedlineRosier, E Loix, S Develter, W Van de Voorde, W Cuypers, E Tytgat, J eng England 2017/07/08 J Forensic Leg Med. 2017 Aug; 50:28-35. doi: 10.1016/j.jflm.2017.06.003. Epub 2017 Jun 19" |
