« Previous AbstractMechanisms that ensure monogamous mating in Saccharomyces cerevisiae    Next AbstractThe National Human Exposure Assessment Survey (NHEXAS) study in Arizona--introduction and preliminary results »

J Chem Ecol

Title:		"Extraction, characterization, and binding analysis of two pheromonally active ligands associated with major urinary protein of house mouse (Mus musculus)"
Author(s):		Robertson DH; Beynon RJ; Evershed RP;
Address:		"Proteolysis Research Group Department of Biochemistry, The University of Liverpool, P.O. Box 147, L69 3BX, Liverpool, UK"
Journal Title:		J Chem Ecol
Year:		1993
Volume:		19
Issue:		7
Page Number:		1405 - 1416
DOI:		10.1007/BF00984885
ISSN/ISBN:		0098-0331 (Print) 0098-0331 (Linking)
Abstract:		"Mouse urine contains substantial quantities of a family of proteins (MUPs) that are members of the lipocalycin family of proteins and that are potentially capable of binding hydrophobic molecules. We have used gas chromatography-mass spectrometry (GC-MS) to characterize two ligands associated with the MUPs, a thiazole and a brevicomin derivative. Previous work has suggested a role for these two ligands as androgen-dependent pheromones. In urine, nearly all of these ligands are protein bound and fractionation of MUPs on Mono-Q anion exchange chromatography indicated some specificity of ligand binding by the MUP subclasses"
Keywords:
Notes:		"PubMed-not-MEDLINERobertson, D H Beynon, R J Evershed, R P eng 1993/07/01 J Chem Ecol. 1993 Jul; 19(7):1405-16. doi: 10.1007/BF00984885"