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Science

Title:		Identification of a neuropeptide hormone that regulates sex pheromone production in female moths
Author(s):		Raina AK; Jaffe H; Kempe TG; Keim P; Blacher RW; Fales HM; Riley CT; Klun JA; Ridgway RL; Hayes DK;
Address:
Journal Title:		Science
Year:		1989
Volume:		244
Issue:		4906
Page Number:		796 - 798
DOI:		10.1126/science.244.4906.796
ISSN/ISBN:		0036-8075 (Print) 0036-8075 (Linking)
Abstract:		"A pheromone biosynthesis activating neuropeptide (PBAN) hormone that controls sex pheromone production in female moths was identified from the brain-subesophageal ganglion complexes of the adult corn earworm, Heliothis zea. PBAN has 33 amino acid residues and a molecular weight of 3900. Its amino acid sequence has no significant homology with any of the fully characterized peptide hormones. The synthetic peptide, at a dose of between 2 and 4 picomoles, induced production of a normal quantity of sex pheromone in ligated H. zea females. The peptide also induced pheromone production in six other species of moths, thus indicating that this or similar peptides may be responsible for the regulation of pheromone production in moths"
Keywords:
Notes:		"PubMed-not-MEDLINERaina, A K Jaffe, H Kempe, T G Keim, P Blacher, R W Fales, H M Riley, C T Klun, J A Ridgway, R L Hayes, D K eng 1989/05/19 Science. 1989 May 19; 244(4906):796-8. doi: 10.1126/science.244.4906.796"