| Title: | Chemosensation: molecular mechanisms in worms and mammals |
| Address: | "Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, 725 North Wolfe Street, PCTB 800, Baltimore, MD 21205, USA.brinda@welchlink.welch.jhu.edu" |
| DOI: | 10.1016/s0168-9525(99)01695-9 |
| ISSN/ISBN: | 0168-9525 (Print) 0168-9525 (Linking) |
| Abstract: | "Communication with the environment and other animals through chemical cues is an essential process for the survival of many multicellular organisms. Specialized signal transduction pathways are employed in chemodetection and the transformation of information into the electrical signals that elicit behaviors. In organisms as diverse as mice and nematodes, similar molecules are involved in the odorant signaling pathways. Studying the mechanisms of signal transduction in these two systems using biochemical, molecular and genetic approaches has elucidated pathways for odor perception and the roles of specific proteins and second messenger molecules in the signaling cascades" |
| Keywords: | Animals Caenorhabditis elegans/physiology Mammals Mice Pheromones/physiology Signal Transduction/physiology Smell/*physiology; |
| Notes: | "MedlinePrasad, B C Reed, R R eng Review England 1999/04/28 Trends Genet. 1999 Apr; 15(4):150-3. doi: 10.1016/s0168-9525(99)01695-9" |
