| Title: | "Chemical Composition of Essential Oils from Different Parts of Zingiberkerrii Craib and Their Antibacterial, Antioxidant, and Tyrosinase Inhibitory Activities" |
| Author(s): | Pintatum A; Laphookhieo S; Logie E; Berghe WV; Maneerat W; |
| Address: | "Center of Chemical Innovation for Sustainability (CIS) and School of Science, Mae Fah Luang University, Chiang Rai 57100, Thailand. Lab Protein Chemistry, Proteomics & Epigenetic Signalling (PPES), Department Biomedical Sciences, University of Antwerp, 2610 Wilrijk, Belgium" |
| ISSN/ISBN: | 2218-273X (Electronic) 2218-273X (Linking) |
| Abstract: | "The essential oils of the fresh rhizomes; flowers; and leaves of Zingiber kerrii Craib were investigated using different extraction techniques; including solid-phase microextraction (SPME), hydrodistillation (HD), and organic solvent (OS), and characterized by gas chromatography-mass spectrometry (GC-MS). A total of 37 SPME; 19 HD; and 36 OS compounds were identified from the rhizome extract of Z. kerrii; with the major components being alpha-pinene; beta-pinene; and terpinen-4-ol; respectively. From the flower extract; 16 SPME; 2 HD; and 10 OS compounds were identified; (E)-caryophyllene was found as a major compound by these techniques. The leaf extract exhibited 20 SPME; 13 HD; and 14 OS compounds; with alpha-pinene; (E)-caryophyllene; and n-hexadecanoic acid being the major compounds; respectively. The rhizome extract showed tyrosinase inhibitory activity of 71.60% and a total phenolic content of 22.4 mg gallic acid/g. The IC(50) values of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) assays were 25.2 microg/mL and 153.6 microg/mL; respectively; and the ferric ion reducing antioxidant power (FRAP) assay value was 318.5 microM ascorbic acid equivalent (AAE)/g extract. The rhizome extract showed weak antibacterial activity. This extract showed no adverse toxicity in human keratinocyte (HaCaT) cell lines at concentrations below 200 microg/mL" |
| Keywords: | Agaricales/enzymology Anti-Bacterial Agents/*chemistry/isolation & purification/pharmacology Antioxidants/*chemistry/isolation & purification/pharmacology Cell Line Enzyme Inhibitors/*chemistry/isolation & purification/pharmacology Flowers/chemistry Human; |
| Notes: | "MedlinePintatum, Aknarin Laphookhieo, Surat Logie, Emilie Berghe, Wim Vanden Maneerat, Wisanu eng PHD59I0050, TRG5880164, and DBG6280007/Thailand Research Fund/International Research Support, Non-U.S. Gov't Switzerland 2020/02/09 Biomolecules. 2020 Feb 4; 10(2):228. doi: 10.3390/biom10020228" |
