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J Int Acad Periodontol

Title:		"Effects of sodium lauryl sulphate (SLS), present in dentifrice, on volatile sulphur compound (VSC) formation in morning bad breath"
Author(s):		Peruzzo DC; Salvador SL; Sallum AW; da Nogueira-Filho GR;
Address:		"Department of Prosthodontics and Periodontics, Dental School of Piracicaba, State University of Campinas, Piracicaba, SP, Brazil. daiaperuzzo@yahoo.com.br"
Journal Title:		J Int Acad Periodontol
Year:		2008
Volume:		10
Issue:		4
Page Number:		130 - 136
DOI:
ISSN/ISBN:		1466-2094 (Print) 1466-2094 (Linking)
Abstract:		"The purpose of the present investigation was to evaluate the effects of sodium lauryl sulphate (SLS), present in a commercial dentifrice, on the formation of volatile sulphur compounds (VSC) and tongue coating in a panel of periodontally healthy subjects. A two-step blinded, crossover, randomized study was carried out in 25 dental students with healthy periodontium; these were divided into two experimental groups: SLS (dentifrice with SLS) and WSLS (dentifrice without SLS). The volunteers received the designated dentifrice and a new toothbrush for a 3x/day brushing regimen for 2 periods of 30 days. A seven-day washout interval was used between the periods. The assessed parameters were: plaque index (PI), gingival index (GI), organoleptic breath (ORG), VSC levels by portable sulphide monitor before (H1) and after (H2) cleaning of the tongue, tongue coating wet weight (TC) and benzoyl-DL-arginine-naphthylamide (BANA) test from tongue coating samples. The intra-group analysis showed a decrease in the median of organoleptic scores from 3 to 2 after 30 days for the SLS group (p < 0.05). The inter-group analysis showed lower values in ORG and H1 for the SLS group (p < 0.05). There was no difference between the amount of TC in SLS and WSLS groups. In the BANA test, the presence of SLS did not affect the BANA number of +/- results (p > 0.05). These findings suggest that sodium lauryl sulphate (SLS), present in dentifrice, appears to prevent VSC formation in morning bad breath regardless of the amount of tongue coating in periodontally healthy subjects"
Keywords:		Adult Benzoylarginine-2-Naphthylamide Cross-Over Studies Dental Plaque Index Dentifrices/*therapeutic use Female Halitosis/metabolism/*prevention & control Humans Male Periodontal Attachment Loss/classification Periodontal Index Periodontal Pocket/classif;
Notes:		"MedlinePeruzzo, Daiane Cristina Salvador, Sergio Luis Sallum, Antonio Wilson da Nogueira-Filho, Getulio Rocha eng Comparative Study Randomized Controlled Trial Research Support, Non-U.S. Gov't England 2008/12/06 J Int Acad Periodontol. 2008 Oct; 10(4):130-6"