| Title: | "N-, O- and S-Heterocycles Synthesis in Deep Eutectic Solvents" |
| Author(s): | Perrone S; Messa F; Troisi L; Salomone A; |
| Address: | "Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali, Universita del Salento, Prov.le Lecce-Monteroni, I-73100 Lecce, Italy. Dipartimento di Chimica, Consorzio C.I.N.M.P.I.S., Universita degli Studi di Bari 'Aldo Moro', Via E. Orabona 4, I-70125 Bari, Italy" |
| DOI: | 10.3390/molecules28083459 |
| ISSN/ISBN: | 1420-3049 (Electronic) 1420-3049 (Linking) |
| Abstract: | "The synthesis of heterocycles is a fundamental area of organic chemistry that offers enormous potential for the discovery of new products with important applications in our daily life such as pharmaceuticals, agrochemicals, flavors, dyes, and, more generally, engineered materials with innovative properties. As heterocyclic compounds find application across multiple industries and are prepared in very large quantities, the development of sustainable approaches for their synthesis has become a crucial objective for contemporary green chemistry committed to reducing the environmental impact of chemical processes. In this context, the present review focuses on the recent methodologies aimed at preparing N-, O- and S-heterocyclic compounds in Deep Eutectic Solvents, a new class of ionic solvents that are non-volatile, non-toxic, easy to prepare, easy to recycle, and can be obtained from renewable sources. Emphasis has been placed on those processes that prioritize the recycling of catalyst and solvent, as they offer the dual benefit of promoting synthetic efficiency while demonstrating environmental responsibility" |
| Keywords: | H-bond catalysis deep eutectic solvents heterocyclic synthesis; |
| Notes: | "PubMed-not-MEDLINEPerrone, Serena Messa, Francesco Troisi, Luigino Salomone, Antonio eng D2464488/Regione Puglia 'Research for Innovation (REFIN)'/ Review Switzerland 2023/04/28 Molecules. 2023 Apr 14; 28(8):3459. doi: 10.3390/molecules28083459" |
