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J Nutr

Title:		Development and validation of a food frequency questionnaire for the assessment of dietary total antioxidant capacity
Author(s):		Pellegrini N; Salvatore S; Valtuena S; Bedogni G; Porrini M; Pala V; Del Rio D; Sieri S; Miglio C; Krogh V; Zavaroni I; Brighenti F;
Address:		"Department of Public Health, University of Parma, Parma, Italy. nicoletta.pelllegrini@unipr.it"
Journal Title:		J Nutr
Year:		2007
Volume:		137
Issue:		1
Page Number:		93 - 98
DOI:		10.1093/jn/137.1.93
ISSN/ISBN:		0022-3166 (Print) 0022-3166 (Linking)
Abstract:		"The total antioxidant capacity (TAC) of the diet may be an important tool to monitor the protective effect of plant foods in epidemiological studies. We developed a semi-quantitative FFQ for the assessment of dietary TAC by 3 different assays, i.e., Trolox equivalent antioxidant capacity (TEAC), total radical-trapping antioxidant parameter (TRAP) and ferric reducing-antioxidant power (FRAP). The FFQ consists of 53 questions about the major sources of dietary TAC in Northern Italy and was validated against a 3-d weighed food record (3D-WR) in 285 individuals (159 males and 126 females) aged 35-88 y and living in the province of Parma (Italy). Plasma TAC was also evaluated in a subgroup of subjects using the TEAC and FRAP assays. The FFQ was associated with 3D-WR (quadratic-weighted kappa = 0.49 for TEAC, 0.53 for TRAP, and 0.49 for FRAP; P < 0.0001) and proved reasonably accurate to classify individuals into quartiles of TAC intake. The FFQ had a good repeatability when readministered after 1 y in 55 subjects (quadratic-weighted kappa for intertertile agreement = 0.66 for TEAC, 0.70 for TRAP and 0.68 for FRAP; P < 0.0001). With both dietary instruments, the main contributors to TAC intake were coffee and tea in women and alcoholic beverages in men, followed by fruits and vegetables in both sexes. Plasma TAC and dietary TAC were not associated. In conclusion, our FFQ has the potential for being used to rank subjects on the basis of their antioxidant intake as determined by dietary TAC in large epidemiological studies. The FFQ should be validated in external populations before being used for research purposes"
Keywords:		"Adult Aged Aged, 80 and over Antioxidants/*pharmacokinetics Body Mass Index *Diet Records *Feeding Behavior Humans Middle Aged Reproducibility of Results *Surveys and Questionnaires;"
Notes:		"MedlinePellegrini, Nicoletta Salvatore, Sara Valtuena, Silvia Bedogni, Giorgio Porrini, Marisa Pala, Valeria Del Rio, Daniele Sieri, Sabina Miglio, Cristiana Krogh, Vittorio Zavaroni, Ivana Brighenti, Furio eng Research Support, Non-U.S. Gov't 2006/12/22 J Nutr. 2007 Jan; 137(1):93-8. doi: 10.1093/jn/137.1.93"