| Title: | Acquired Color Vision Defects and Hexane Exposure: A Study of San Francisco Bay Area Automotive Mechanics |
| Author(s): | Beckman S; Eisen EA; Bates MN; Liu S; Haegerstrom-Portnoy G; Hammond SK; |
| ISSN/ISBN: | 1476-6256 (Electronic) 0002-9262 (Print) 0002-9262 (Linking) |
| Abstract: | "Occupational exposure to solvents, including n-hexane, has been associated with acquired color vision defects. Blue-yellow defects are most common and may be due to neurotoxicity or retinal damage. Acetone may potentiate the neurotoxicity of n-hexane. We present results on nonhexane solvent and hexane exposure and color vision from a cross-sectional study of 835 automotive repair workers in the San Francisco Bay Area, California (2007-2013). Cumulative exposure was estimated from self-reported work history, and color vision was assessed using the Lanthony desaturated D-15 panel test. Log-binomial regression was used to estimate prevalence ratios for color vision defects. Acquired color vision defects were present in 29% of participants, of which 70% were blue-yellow. Elevated prevalence ratios were found for nonhexane solvent exposure, with a maximum of 1.31 (95% confidence interval (CI): 0.86, 2.00) for blue-yellow. Among participants aged |
| Keywords: | Adult Age Factors Aged *Automobiles Color Vision Defects/*chemically induced/classification Cross-Sectional Studies Environmental Monitoring Health Behavior Hexanes/*adverse effects/analysis Humans Male Middle Aged Occupational Diseases/classification/*ep; |
| Notes: | "MedlineBeckman, Stella Eisen, Ellen A Bates, Michael N Liu, Sa Haegerstrom-Portnoy, Gunilla Hammond, S Katharine eng R01 ES014049/ES/NIEHS NIH HHS/ T42 OH008429/OH/NIOSH CDC HHS/ Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S. 2016/05/18 Am J Epidemiol. 2016 Jun 1; 183(11):969-76. doi: 10.1093/aje/kwv328. Epub 2016 May 17" |
