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« Previous Abstract"Inhibitory action of (4S,6S,7R)-isomer to pheromonal activity of serricornin, (4S,6S,7S)-7-Hydroxy-4,6-dimethyl-3-nonanone"    Next Abstract"Isolation and structure of the sex pheromone inhibitor, iPD1, excreted by Streptococcus faecalis donor strains harboring plasmid pPD1" »

FEBS Lett


Title:"Isolation and structure of the Streptococcus faecalis sex pheromone, cAM373"
Author(s):Mori M; Tanaka H; Sakagami Y; Isogai A; Fujino M; Kitada C; White BA; An FY; Clewell DB; Suzuki A;
Address:
Journal Title:FEBS Lett
Year:1986
Volume:206
Issue:1
Page Number:69 - 72
DOI: 10.1016/0014-5793(86)81342-4
ISSN/ISBN:0014-5793 (Print) 0014-5793 (Linking)
Abstract:"The Streptococcus faecalis sex pheromone, cAM373, which induces a mating response of donor cells harboring plasmid pAM373 and is also produced by Staphylococcus aureus, was isolated and its structure determined. Supernatant from an overnight culture of a recipient strain was subjected to successive purification procedures, and 4.4 micrograms cAM373 was obtained. The isolated pheromone showed activity at a concentration as low as 5 X 10(-11) M. Sequence analysis indicated that cAM373 was a heptapeptide, H-Ala-Ile-Phe-Ile-Leu-Ala-Ser-OH, and that its Mr was 733. A synthetic replicate of the peptide showed the same biological activity and chromatographic behavior as the native cAM373"
Keywords:Amino Acid Sequence Enterococcus faecalis/*analysis Oligopeptides/*isolation & purification Pheromones;
Notes:"MedlineMori, M Tanaka, H Sakagami, Y Isogai, A Fujino, M Kitada, C White, B A An, F Y Clewell, D B Suzuki, A eng Research Support, Non-U.S. Gov't England 1986/09/29 FEBS Lett. 1986 Sep 29; 206(1):69-72. doi: 10.1016/0014-5793(86)81342-4"

 
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