| Title: | Chemical composition and in vitro antibacterial activity of the essential oil of Phthirusa adunca from Venezuelan Andes |
| Author(s): | Mora FD; Rios N; Rojas LB; Diaz T; Velasco J; Carmona JA; Silva B; |
| Address: | "Department of Pharmacognosy and Organic Medicaments, Facultad de Farmacia y Bioanalisis, University of Los Andes, Merida, Venezuela 5101. flormv@ula.ve" |
| ISSN/ISBN: | 1934-578X (Print) 1555-9475 (Linking) |
| Abstract: | "In this paper, preliminary studies on the chemical characterization of Phthirusa adunca Meyer essential oil, obtained by hydrodistillation, is presented. The separation of the components was performed by GC-MS. Twenty-three compounds (94.5% of the sample) were identified of which the three major ones (76% of the sample) were beta-phellandrene (38.1%), germacrene D (26.8%) and beta-pinene (11.5%). The essential oil showed a broad spectrum of activity against Salmonella Typhi CDC 57 (100 microg/mL), Staphylococcus aureus ATCC 25923 (200 microg/mL), Enterococcus faecalis ATCC 29212 (250 microg/mL), Escherichia coli ATCC 25922 y Klebsiella pneumoniae ATCC 23357 (500 microg/mL). This is the first report on the composition and activity of the essential oil of this species" |
| Keywords: | "Anti-Bacterial Agents/*chemistry/*pharmacology Bacteria/drug effects Gas Chromatography-Mass Spectrometry Loranthaceae/*chemistry Microbial Sensitivity Tests Monoterpenes/chemistry/*isolation & purification/pharmacology Oils, Volatile/*chemistry/*pharmaco;" |
| Notes: | "MedlineMora, Flor D Rios, Nurby Rojas, Luis B Diaz, Tulia Velasco, Judith Carmona, Juan A Silva, Bladimiro eng Research Support, Non-U.S. Gov't 2011/08/13 Nat Prod Commun. 2011 Jul; 6(7):1051-3" |
