| Title: | A natural deep eutectic solvent - protonated L-proline-xylitol - based stationary phase for gas chromatography |
| Author(s): | Momotko M; Luczak J; Przyjazny A; Boczkaj G; |
| Address: | "Gdansk University of Technology, Faculty of Chemistry, Department of Process Engineering and Chemical Technology, 80 - 233 Gdansk, G. Narutowicza St. 11/12, Poland. Electronic address: malwina.momotko@wp.pl. Gdansk University of Technology, Faculty of Chemistry, Department of Process Engineering and Chemical Technology, 80 - 233 Gdansk, G. Narutowicza St. 11/12, Poland; Advanced Materials Center, Gdansk University of Technology, 80 - 233 Gdansk, G. Narutowicza St. 11/12, Poland. Kettering University, 1700 University Avenue, Flint, MI 48504, USA. Advanced Materials Center, Gdansk University of Technology, 80 - 233 Gdansk, G. Narutowicza St. 11/12, Poland; Gdansk University of Technology, Faculty of Civil and Environmental Engineering, Department of Sanitary Engineering, 80 - 233 Gdansk, G. Narutowicza St. 11/12, Poland. Electronic address: grzegorz.boczkaj@pg.edu.pl" |
| DOI: | 10.1016/j.chroma.2022.463238 |
| ISSN/ISBN: | 1873-3778 (Electronic) 0021-9673 (Linking) |
| Abstract: | "The paper presents a new kind of stationary phase for gas chromatography based on deep eutectic solvents (DES) in the form of a mixture of L-proline (protonated with hydrochloric acid) as a hydrogen bond acceptor (HBA) and xylitol as a hydrogen bond donor (HBD) in a molar ratio of HBA:HBD 5:1. DES immobilized on a silanized chromatographic support was tested by gas chromatography (GC) in order to determine its resolving power for volatile organic compounds. Studies have demonstrated the suitability of this type of DES as a stationary phase for GC. The Rohrschneider-McReynolds constants were determined for the synthesized DES, revealing that it is a polar stationary phase (Sigma(DeltaI) = 1717). The selectivity of DES is influenced by the presence of hydroxyl groups in the xylitol structure capable of forming hydrogen bonds of a donor nature and the proton acceptor properties of the protonated L-proline structure. The presence of additional interactions is brought about by the presence of the carboxyl group. As a result, the retention of alcohols is several times higher (200-670%) than the expected value based on their boiling points. A significant increase in retention (400-970%) was also found for pyridine derivatives. The developed DES stationary phase is characterized by very good repeatability of retention and stability (up to 140 degrees C). The efficiency of the prepared columns (6300-11300 theoretical plates/m) and the selectivity of the DES stationary phase are competitive with the commercial products" |
| Keywords: | "Chromatography, Gas/methods *Deep Eutectic Solvents Proline Solvents/chemistry *Xylitol/chemistry Hydrogen bond Molecular interactions Natural deep eutectic solvent (NADES) Separation techniques Volatile organic compounds (VOCs);" |
| Notes: | "MedlineMomotko, Malwina Luczak, Justyna Przyjazny, Andrzej Boczkaj, Grzegorz eng Netherlands 2022/07/06 J Chromatogr A. 2022 Aug 2; 1676:463238. doi: 10.1016/j.chroma.2022.463238. Epub 2022 Jun 12" |
