Title: | Aerosol size distribution measurement of electronic cigarette emissions using combined differential mobility and inertial impaction methods: Smoking machine and puff topography influence |
Author(s): | Mikheev VB; Ivanov A; Lucas EA; South PL; Colijn HO; Clark PI; |
Address: | "Battelle Memorial Institute, Columbus, Ohio, USA. Center for Electron Microscopy and Analysis, Ohio State University, Columbus, Ohio, USA. University of Maryland, College Park, Maryland, USA" |
DOI: | 10.1080/02786826.2018.1513636 |
ISSN/ISBN: | 0278-6826 (Print) 0278-6826 (Linking) |
Abstract: | "A combination of a real-time high resolution aerosol differential mobility spectrometer (DMS500) and an electrical low pressure impactor (used as a traditional impactor) was applied to simultaneously collect real-time data and analyze particle size by weighing the mass of the aerosol collected on the impactor stages. Nonrefillable fixed-power as well as refillable and power adjustable e-cigarettes (e-cigs) were tested at various puffing flow rates. Two types of smoking machines were used: a smoke cycle simulator that provides instantaneous straight sample delivery to the analyzer and a Human Profile Pump that utilizes two synchronized pistons and operates by sample pull-push mode. Chemical analysis of the major components of e-liquid (propylene glycol, vegetable glycerol, water, and nicotine) was made using a proton nuclear magnetic resonance method. Limited amounts of samples collected on impactor stages were analyzed by liquid chromatography time-of-flight mass-spectrometry to find newly formed semi- or low-volatile organic compounds in e-cig aerosol and by transmission electron microscopy to check for the presence of nanoparticles in e-cig emissions. Differential mobility and inertial impaction methods showed comparable particle size results. Method of aerosol generation (type of the smoking machine) as well as puffing topography affected the e-cig particle size. Newly formed semi- or low-volatile organic compounds as well as metal nanoparticles were found in e-cig aerosol" |
Notes: | "PubMed-not-MEDLINEMikheev, Vladimir B Ivanov, Alexander Lucas, Eric A South, Patrick L Colijn, Hendrik O Clark, Pamela I eng P50 CA180523/CA/NCI NIH HHS/ 2018/01/01 Aerosol Sci Technol. 2018; 52(11):1233-1248. doi: 10.1080/02786826.2018.1513636. Epub 2018 Sep 14" |