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Annu Rev Microbiol


Title:Cell polarity and morphogenesis in budding yeast
Author(s):Madden K; Snyder M;
Address:"Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06520-8103, USA"
Journal Title:Annu Rev Microbiol
Year:1998
Volume:52
Issue:
Page Number:687 - 744
DOI: 10.1146/annurev.micro.52.1.687
ISSN/ISBN:0066-4227 (Print) 0066-4227 (Linking)
Abstract:"Eukaryotic cells respond to intracellular and extracellular cues to direct asymmetric cell growth and division. The yeast Saccharomyces cerevisiae undergoes polarized growth at several times during budding and mating and is a useful model organism for studying asymmetric growth and division. In recent years, many regulatory and cytoskeletal components important for directing and executing growth have been identified, and molecular mechanisms have been elucidated in yeast. Key signaling pathways that regulate polarization during the cell cycle and mating response have been described. Since many of the components important for polarized cell growth are conserved in other organisms, the basic mechanisms mediating polarized cell growth are likely to be universal among eukaryotes"
Keywords:"Calcium-Calmodulin-Dependent Protein Kinases/metabolism Cell Cycle/physiology Cell Division/physiology *Cell Polarity Cyclin G Cyclin-Dependent Kinases/metabolism Cyclins/physiology Cytoskeleton/physiology Fungal Proteins/metabolism Genes, Fungal Pheromon;"
Notes:"MedlineMadden, K Snyder, M eng Review 1999/01/19 Annu Rev Microbiol. 1998; 52:687-744. doi: 10.1146/annurev.micro.52.1.687"

 
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