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Fish Physiol Biochem

Title:		Mianserin affects alarm reaction to conspecific chemical alarm cues in Nile tilapia
Author(s):		Barreto RE;
Address:		"Department of Physiology, CAUNESP, Institute of Biosciences of Botucatu, UNESP, Rubiao Jr s/n, Sao Paulo, 18618-970, Brazil. rebarreto@yahoo.com"
Journal Title:		Fish Physiol Biochem
Year:		2017
Volume:		20160823
Issue:		1
Page Number:		193 - 201
DOI:		10.1007/s10695-016-0279-2
ISSN/ISBN:		1573-5168 (Electronic) 0920-1742 (Linking)
Abstract:		"In this study, I show that mianserin, a chemical with serotonin and adrenoceptor antagonist activities, increases fish vulnerability to a potential predator threat, when prey fish must deal with this threat based on conspecific chemical alarm cues. For that, I evaluated whether mianserin, diluted in the water, influences the behavioral responses of Nile tilapia (Oreochromis niloticus) to conspecific skin extract (chemical alarm cues). I found that, while mianserin did not abolished antipredator responses, this drug mitigates some components of this defensive reaction. Thus, a potential decrease in serotonin and adrenergic activities reduces the ability of dealing with predators when perceiving conspecific chemical alarm cues"
Keywords:		"Adrenergic alpha-Antagonists/*pharmacology Animals Behavior, Animal/*drug effects Cichlids/physiology Cues Female Male Mianserin/*pharmacology Pheromones/*pharmacology Serotonin Antagonists/*pharmacology Skin/*chemistry Swimming Alarm substance Anxiety Ch;"
Notes:		"MedlineBarreto, Rodrigo Egydio eng Netherlands 2016/08/25 Fish Physiol Biochem. 2017 Feb; 43(1):193-201. doi: 10.1007/s10695-016-0279-2. Epub 2016 Aug 23"