| Title: | "Cu-Catalyzed Dual C-O Bonds Cleavage of Cyclic Ethers with Carboxylic Acids, NaI, and TMSCF(3) to Give Iodoalkyl Ester" |
| Author(s): | Lu D; Guan W; Yang X; Wang Y; Kambe N; Qiu R; |
| Address: | "State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China. Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan" |
| DOI: | 10.1021/acs.orglett.2c00732 |
| ISSN/ISBN: | 1523-7052 (Electronic) 1523-7052 (Linking) |
| Abstract: | "Herein, by dual C-O bond cleavage of cyclic ethers with Cu catalysis, we eventually led to the development of a selective three-component coupling of commercially available chemicals, carboxylic acids, ethers, and halogens to synthesize more than 70 iodoalkyl esters in the presence of TMSCF(3). This allows for the concise synthesis of highly functionalized iodoalkyl esters directly. And the synthetic insect pheromones were also disclosed" |
| Keywords: | "*Carboxylic Acids/chemistry Catalysis *Esters/chemistry Ethers/chemistry Ethers, Cyclic Hydrocarbons, Fluorinated Silanes;" |
| Notes: | "MedlineLu, Dong Guan, Wenjian Yang, Xiaogang Wang, Yuzhi Kambe, Nobuaki Qiu, Renhua eng Research Support, Non-U.S. Gov't 2022/04/09 Org Lett. 2022 Apr 22; 24(15):2826-2831. doi: 10.1021/acs.orglett.2c00732. Epub 2022 Apr 8" |
