| Title: | The formation mechanism of antibiotic-resistance genes associated with bacterial communities during biological decomposition of household garbage |
| Author(s): | Liang Z; Zhang Y; He T; Yu Y; Liao W; Li G; An T; |
| Address: | "Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Guangzhou Key Laboratory Environmental Catalysis and Pollution Control, School of Environmental Science and Engineering, Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou, 510006, China. Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Guangzhou Key Laboratory Environmental Catalysis and Pollution Control, School of Environmental Science and Engineering, Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou, 510006, China. Electronic address: ligy1999@gdut.edu.cn" |
| DOI: | 10.1016/j.jhazmat.2020.122973 |
| ISSN/ISBN: | 1873-3336 (Electronic) 0304-3894 (Linking) |
| Abstract: | "Food wastes are significant reservoir of antibiotic-resistance genes (ARGs) and antibiotic-resistant bacteria (ARB) available for exchange with clinical pathogens. However, food wastes-related changes of antibiotic resistance in long-period decomposition have been overlooked. Here, we evaluated the comprehensive ARG profile and its association with microbial communities, explained how this might vary with household garbage decomposition. Average of 128, 150 and 91 ARGs were detected in meat, vegetable and fruit wastes, respectively, with multidrug and tetracycline as the predominant ARG types. ARG abundance significantly increased at initial stage of waste fermentation and then decreased. High abundance of Eubacterium-coprostanoligenes, Sporanaerobacter, Peptoniphilus, Peptostreptococcus might be explained for the high relative abundance of ARGs in meat, while high abundance of Advenella, Prevotella, Solobacterium was attributed to the high diversity of ARGs in vegetables. Significant correlations were observed among volatile organic compounds, mobile genetic elements and ARGs, implying that they might contribute to transfer and transport of ARGs. Network analysis revealed that aph(2')-Id-01, acrA-05, tetO-1 were potential ARG indicators, while Hathewaya, Paraclostridium and Prevotellaceae were possible hosts of ARGs. Our work might unveil underlining mechanism of the effects of food wastes decomposition on development and spread of ARGs in environment and also clues to ARG mitigation" |
| Keywords: | "Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors *Anti-Bacterial Agents Bacteria/genetics Drug Resistance, Microbial/genetics *Genes, Bacterial Antibiotic resistance genes Food wastes decomposition Microbial community Mobile genet;" |
| Notes: | "MedlineLiang, Zhishu Zhang, Yuna He, Tao Yu, Yun Liao, Wen Li, Guiying An, Taicheng eng Research Support, Non-U.S. Gov't Netherlands 2020/06/04 J Hazard Mater. 2020 Nov 5; 398:122973. doi: 10.1016/j.jhazmat.2020.122973. Epub 2020 May 21" |
