| Title: | Environment and the development of severe asthma in inner city population |
| Author(s): | Lee JX; Phipatanakul W; Gaffin JM; |
| Address: | "Division of Pulmonary Medicine, Boston Children's Hospital. Division of allergy and immunology, Boston Children's Hospital. Harvard Medical School, Boston, Massachusetts, USA" |
| Journal Title: | Curr Opin Allergy Clin Immunol |
| DOI: | 10.1097/ACI.0000000000000890 |
| ISSN/ISBN: | 1473-6322 (Electronic) 1528-4050 (Print) 1473-6322 (Linking) |
| Abstract: | "PURPOSE OF REVIEW: Higher asthma prevalence and morbidity are seen in inner-city areas, disproportionately affecting low-income families living in substandard housing. Children within these families experience more frequent asthma exacerbations, acute care and emergency department visits, and hospitalizations, thus characterizing severe asthma. In this review, we assess recent published literature focused on indoor and outdoor exposures that contribute to the development and morbidity of asthma. RECENT FINDINGS: Many urban environmental exposures contribute to asthma burden, including tobacco/e-cigarette smoke, pest allergens, molds, and possibly synthetic chemicals such as phthalates and bisphenol A, radon, and volatile organic compounds. Individuals living in inner-city areas also experience higher levels of air pollutants and ambient heat, further perpetuating asthma incidence and severity. SUMMARY: This article summarizes the latest advances and provides direction for future research on risk factors, interventions, and public policy to help alleviate the burden of asthma due to urban environment exposures" |
| Keywords: | "Child Humans *Electronic Nicotine Delivery Systems *Asthma/epidemiology Environmental Exposure/adverse effects Allergens/adverse effects Morbidity Urban Population *Air Pollution, Indoor/adverse effects/analysis;" |
| Notes: | "MedlineLee, Julia X Phipatanakul, Wanda Gaffin, Jonathan M eng R01 ES030100/ES/NIEHS NIH HHS/ K24 AI106822/AI/NIAID NIH HHS/ U01 AI152033/AI/NIAID NIH HHS/ U01 AI160087/AI/NIAID NIH HHS/ Research Support, N.I.H., Extramural Review 2023/02/03 Curr Opin Allergy Clin Immunol. 2023 Apr 1; 23(2):179-184. doi: 10.1097/ACI.0000000000000890. Epub 2023 Jan 12" |
