| Title: | Exposure to Disinfectants and Cleaning Products and Respiratory Health of Workers and Children in Daycares: The CRESPI Cohort Protocol |
| Author(s): | Le Moual N; Dumas O; Bonnet P; Eworo Nchama A; Le Bot B; Sevin E; Pin I; Siroux V; Mandin C; The Crespi Study G; |
| Address: | "Universite Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Equipe d'Epidemiologie Respiratoire Integrative, CESP, 94807 Villejuif, France. Scientific and Technical Center for Building (CSTB), Indoor Environment Quality Unit, 77420 Champs-sur-Marne, France. Irset (Institut de Recherche en Sante, Environnement et Travail)-UMR_S 1085, Inserm, Ecole des Hautes Etudes en Sante Publique (EHESP), University of Rennes, 35000 Rennes, France. EPICONCEPT, 75011 Paris, France. Team of Environmental Epidemiology Applied to the Development and Respiratory Health, Institute for Advanced Biosciences, Inserm U 1209, CNRS UMR 5309, Universite Grenoble Alpes, 38000 Grenoble, France" |
| Journal Title: | Int J Environ Res Public Health |
| ISSN/ISBN: | 1660-4601 (Electronic) 1661-7827 (Print) 1660-4601 (Linking) |
| Abstract: | "Although cleaning tasks are frequently performed in daycare, no study has focused on exposures in daycares in relation to respiratory health. The CRESPI cohort is an epidemiological study among workers (n~320) and children (n~540) attending daycares. The purpose is to examine the impact of daycare exposures to disinfectants and cleaning products (DCP) on the respiratory health of workers and children. A sample of 108 randomly selected daycares in the region of Paris has been visited to collect settled dust to analyze semi-volatile organic compounds and microbiota, as well as sample indoor air to analyze aldehydes and volatile organic compounds. Innovative tools (smartphone applications) are used to scan DCP barcodes in daycare and inform their use; a database then matches the barcodes with the products' compositions. At baseline, workers/parents completed a standardized questionnaire, collecting information on DCP used at home, respiratory health, and potential confounders. Follow-up regarding children's respiratory health (monthly report through a smartphone application and biannual questionnaires) is ongoing until the end of 2023. Associations between DCP exposures and the respiratory health of workers/children will be evaluated. By identifying specific environments or DCP substances associated with the adverse respiratory health of workers and children, this longitudinal study will contribute to the improvement of preventive measures" |
| Keywords: | Humans Child *Disinfectants/analysis *Occupational Exposure/analysis *Volatile Organic Compounds/analysis Longitudinal Studies Dust asthma environmental and occupational exposures epidemiology indoor air quality settled dust; |
| Notes: | "MedlineLe Moual, Nicole Dumas, Orianne Bonnet, Pierre Eworo Nchama, Anastasie Le Bot, Barbara Sevin, Etienne Pin, Isabelle Siroux, Valerie Mandin, Corinne The Crespi Study Group eng Research Support, Non-U.S. Gov't Switzerland 2023/05/27 Int J Environ Res Public Health. 2023 May 21; 20(10):5903. doi: 10.3390/ijerph20105903" |
