| Title: | Characterization of Cyclodextrin/Volatile Inclusion Complexes: A Review |
| Author(s): | Kfoury M; Landy D; Fourmentin S; |
| Address: | "Bioactive Molecules Research Laboratory, Doctoral School of Sciences and Technologies, Faculty of Sciences II, Lebanese University, Fanar, Lebanon. mirianakfoury@hotmail.com. Unite de Chimie Environnementale et Interactions sur le Vivant (UCEIV), EA 4492, SFR Condorcet FR CNRS 3417, Universite du Littoral-Cote d'Opale (ULCO), 59140 Dunkerque, France. landy@univ-littoral.fr. Unite de Chimie Environnementale et Interactions sur le Vivant (UCEIV), EA 4492, SFR Condorcet FR CNRS 3417, Universite du Littoral-Cote d'Opale (ULCO), 59140 Dunkerque, France. lamotte@univ-littoral.fr" |
| DOI: | 10.3390/molecules23051204 |
| ISSN/ISBN: | 1420-3049 (Electronic) 1420-3049 (Linking) |
| Abstract: | "Cyclodextrins (CDs) are a family of cyclic oligosaccharides that constitute one of the most widely used molecular hosts in supramolecular chemistry. Encapsulation in the hydrophobic cavity of CDs positively affects the physical and chemical characteristics of the guests upon the formation of inclusion complexes. Such a property is interestingly employed to retain volatile guests and reduce their volatility. Within this scope, the starting crucial point for a suitable and careful characterization of an inclusion complex is to assess the value of the formation constant (K(f)), also called stability or binding constant. This task requires the application of the appropriate analytical method and technique. Thus, the aim of the present paper is to give a general overview of the main analytical tools used for the determination of K(f) values for CD/volatile inclusion complexes. This review emphasizes on the advantages, inconvenients and limits of each applied method. A special attention is also dedicated to the improvement of the current methods and to the development of new techniques. Further, the applicability of each technique is illustrated by a summary of data obtained from the literature" |
| Keywords: | "Carbon Chromatography, Gas Cyclodextrins/*chemistry Models, Chemical Solubility Spectrum Analysis Volatile Organic Compounds/*chemistry Hplc Itc Nmr Sh-gc Toc UV-Visible cyclodextrin fluorescence formation constant phase solubility volatiles;" |
| Notes: | "MedlineKfoury, Miriana Landy, David Fourmentin, Sophie eng Review Switzerland 2018/05/19 Molecules. 2018 May 17; 23(5):1204. doi: 10.3390/molecules23051204" |
