| Title: | A model-based analysis of chemical and temporal patterns of cuticular hydrocarbons in male Drosophila melanogaster |
| Author(s): | Kent C; Azanchi R; Smith B; Chu A; Levine J; |
| Address: | "Department of Biology, University of Toronto at Mississauga, Mississauga, Ontario, Canada" |
| DOI: | 10.1371/journal.pone.0000962 |
| ISSN/ISBN: | 1932-6203 (Electronic) 1932-6203 (Linking) |
| Abstract: | "Drosophila Cuticular Hydrocarbons (CH) influence courtship behaviour, mating, aggregation, oviposition, and resistance to desiccation. We measured levels of 24 different CH compounds of individual male D. melanogaster hourly under a variety of environmental (LD/DD) conditions. Using a model-based analysis of CH variation, we developed an improved normalization method for CH data, and show that CH compounds have reproducible cyclic within-day temporal patterns of expression which differ between LD and DD conditions. Multivariate clustering of expression patterns identified 5 clusters of co-expressed compounds with common chemical characteristics. Turnover rate estimates suggest CH production may be a significant metabolic cost. Male cuticular hydrocarbon expression is a dynamic trait influenced by light and time of day; since abundant hydrocarbons affect male sexual behavior, males may present different pheromonal profiles at different times and under different conditions" |
| Keywords: | "Animals Circadian Rhythm/physiology Drosophila melanogaster/*metabolism/physiology Hydrocarbons/*analysis Light Male *Models, Theoretical Sex Attractants/analysis Sexual Behavior, Animal/physiology/radiation effects;" |
| Notes: | "MedlineKent, Clement Azanchi, Reza Smith, Ben Chu, Adrienne Levine, Joel eng Research Support, Non-U.S. Gov't 2007/09/27 PLoS One. 2007 Sep 26; 2(9):e962. doi: 10.1371/journal.pone.0000962" |
