Title: | Biting activity by Aedes egypti mosquitoes in guinea-pigs. An experimental model for screening the effect of some systemically administered compounds |
Author(s): | Kelkar VV; Pandya AP; Metha NR; |
ISSN/ISBN: | 0041-3232 (Print) 0041-3232 (Linking) |
Abstract: | "The Aedes egypti mosquito fed consistently on guinea-pigs in a 2-hour period (n = 61), the mean percent feeding rate (+/- S.D.) being 88.84 +/- 9.32. Of a total of 34 different compounds systematally administered in guinea-pigs and tested for their effect on the mosquito biting rate using the above model, five: heparin, sodium fluoride, aminocaproic acid, thiourea and dithiocarb partially reduced the biting rate. The results are consistent with the view that certain aminoacids or proteins of blood or tissues serve as 'pheromones' attracting the mosquito to guinea-pigs" |
Keywords: | Aedes/*drug effects Aminocaproic Acid/pharmacology Animals Female Guinea Pigs Heparin/pharmacology Odorants Pheromones/*blood Plant Extracts/pharmacology Sodium Fluoride/pharmacology Taste/drug effects Thiocarbamates/pharmacology Thiourea/pharmacology; |
Notes: | "MedlineKelkar, V V Pandya, A P Metha, N R eng Netherlands 1979/09/01 Trop Geogr Med. 1979 Sep; 31(3):415-9" |