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Trends Genet

Title:		Drosophila Chemoreceptors: A Molecular Interface Between the Chemical World and the Brain
Author(s):		Joseph RM; Carlson JR;
Address:		"Department of Molecular, Cellular, and Developmental Biology, Yale University, PO Box 208103, New Haven, CT 06520-8103, USA. Department of Molecular, Cellular, and Developmental Biology, Yale University, PO Box 208103, New Haven, CT 06520-8103, USA. Electronic address: john.carlson@yale.edu"
Journal Title:		Trends Genet
Year:		2015
Volume:		20151022
Issue:		12
Page Number:		683 - 695
DOI:		10.1016/j.tig.2015.09.005
ISSN/ISBN:		0168-9525 (Print) 0168-9525 (Linking)
Abstract:		"Chemoreception is essential for survival. Feeding, mating, and avoidance of predators depend on detection of sensory cues. Drosophila contains diverse families of chemoreceptors that detect odors, tastants, pheromones, and noxious stimuli, including receptors of the odor receptor (Or), gustatory receptor (Gr), ionotropic receptor (IR), Pickpocket (Ppk), and Trp families. We consider recent progress in understanding chemoreception in the fly, including the identification of new receptors, the discovery of novel biological functions for receptors, and the localization of receptors in unexpected places. We discuss major unsolved problems and suggest areas that may be particularly ripe for future discoveries, including the roles of these receptors in driving the circuits and behaviors that are essential to the survival and reproduction of the animal"
Keywords:		"Animals Brain/*physiology Drosophila melanogaster/*physiology Receptors, Cell Surface/genetics/*physiology Smell Taste gustatory receptor ionotropic glutamate receptor odor receptor olfaction olfactory receptor neuron;"
Notes:		"MedlineJoseph, Ryan M Carlson, John R eng R01 DC002174/DC/NIDCD NIH HHS/ R01 DC004729/DC/NIDCD NIH HHS/ R01 DC011697/DC/NIDCD NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review England 2015/10/20 Trends Genet. 2015 Dec; 31(12):683-695. doi: 10.1016/j.tig.2015.09.005. Epub 2015 Oct 22"