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Phytochemistry

Title:		"Isoschaftoside, a C-glycosylflavonoid from Desmodium uncinatum root exudate, is an allelochemical against the development of Striga"
Author(s):		Hooper AM; Tsanuo MK; Chamberlain K; Tittcomb K; Scholes J; Hassanali A; Khan ZR; Pickett JA;
Address:		"Biological Chemistry Department, Centre for Sustainable Pest and Disease Management, Rothamsted Research, Harpenden, Herts, UK. tony.hooper@bbsrc.ac.uk"
Journal Title:		Phytochemistry
Year:		2010
Volume:		20100306
Issue:		8-Sep
Page Number:		904 - 908
DOI:		10.1016/j.phytochem.2010.02.015
ISSN/ISBN:		1873-3700 (Electronic) 0031-9422 (Linking)
Abstract:		"In East African small-holder farming of maize, the cattle forage legume, Desmodium uncinatum is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Bioassay-guided fractionation of the root extract of D. uncinatum revealed isoschaftoside to be the main compound in the most potent fraction inhibiting growth of germinated S. hermonthica radicles. Bioassays repeated with isoschaftoside isolated from a different plant source, Passiflora incarnata, proved it to be a biologically active component. Analysis of the root exudates produced by hydroponically grown D. uncinatum showed isoschaftoside to be present in the hydroponic media at biologically active concentrations of 10-100 nM"
Keywords:		"Africa, Eastern Animals Cattle Flavonoids/chemistry/*isolation & purification/pharmacology Glycosides/chemistry/*isolation & purification/pharmacology Molecular Structure Pheromones/pharmacology Plant Diseases/parasitology Plant Exudates/chemistry Plant R;"
Notes:		"MedlineHooper, Antony M Tsanuo, Muniru K Chamberlain, Keith Tittcomb, Kay Scholes, Julie Hassanali, Ahmed Khan, Zeyaur R Pickett, John A eng BB/E015956/1/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom BB/F003986/1/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom Research Support, Non-U.S. Gov't England 2010/03/10 Phytochemistry. 2010 Jun; 71(8-9):904-8. doi: 10.1016/j.phytochem.2010.02.015. Epub 2010 Mar 6"