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Am J Emerg Med

Title:		Garlic burn injuries- a systematic review of reported cases
Author(s):		Hitl M; Kladar N; Gavaric N; Srdenovic Conic B; Bozin B;
Address:		"University of Novi Sad, Faculty of Medicine, Department of Pharmacy, Hajduk Veljkova 3, 21000, Novi Sad, Serbia. Electronic address: maja.bekut@mf.uns.ac.rs. University of Novi Sad, Faculty of Medicine, Department of Pharmacy, Hajduk Veljkova 3, 21000, Novi Sad, Serbia. Electronic address: nebojsa.kladar@mf.uns.ac.rs. University of Novi Sad, Faculty of Medicine, Department of Pharmacy, Hajduk Veljkova 3, 21000, Novi Sad, Serbia. Electronic address: neda.gavaric@mf.uns.ac.rs. University of Novi Sad, Faculty of Medicine, Department of Pharmacy, Hajduk Veljkova 3, 21000, Novi Sad, Serbia. Electronic address: branislava.srdjenovic-conic@mf.uns.ac.rs. University of Novi Sad, Faculty of Medicine, Department of Pharmacy, Hajduk Veljkova 3, 21000, Novi Sad, Serbia. Electronic address: biljana.bozin@mf.uns.ac.rs"
Journal Title:		Am J Emerg Med
Year:		2021
Volume:		20210131
Issue:
Page Number:		5 - 10
DOI:		10.1016/j.ajem.2021.01.039
ISSN/ISBN:		1532-8171 (Electronic) 0735-6757 (Linking)
Abstract:		"Medicinal plants have many beneficial effects on human health. Garlic (Allium sativum, Alliaceae) is one of the most famous herbal species, used for various diseases and conditions. Unfortunately, garlic is also associated with adverse effects, including cutaneous manifestations. In this review, burn injuries caused by application of raw garlic are reported. Searching through PubMed, Google Scholar and ResearchGate, a total of 32 articles with 39 patients were found. Demographics of patients, reasons for garlic use, details on garlic application, as well as description of burns and its treatment are thoroughly described and discussed. In most of the cases, garlic caused second-degree burns, although some circumstances can cause formation of necrotic tissue. Various body parts were affected, legs being most common. The chemistry of garlic is also presented, with focus on volatile organic sulfur compounds, which also seem to be responsible for burns formation. Treatment of garlic burns was mainly symptomatic, and various types of drugs were used. Although not commonly expected, garlic should be taken into consideration as causative agents of burns by treating doctors, and patients should be advised against application of fresh garlic onto skin and mucosa"
Keywords:		"Burns, Chemical/*etiology Garlic/*adverse effects/*chemistry Humans Phytotherapy/*adverse effects Allium sativum Burns Garlic Herbal Skin;"
Notes:		"MedlineHitl, Maja Kladar, Nebojsa Gavaric, Neda Srdenovic Conic, Branislava Bozin, Biljana eng Research Support, Non-U.S. Gov't Systematic Review 2021/02/12 Am J Emerg Med. 2021 Jun; 44:5-10. doi: 10.1016/j.ajem.2021.01.039. Epub 2021 Jan 31"