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Mol Cell Biol

Title:		"Multiple regulation of STE2, a mating-type-specific gene of Saccharomyces cerevisiae"
Author(s):		Hartig A; Holly J; Saari G; MacKay VL;
Address:
Journal Title:		Mol Cell Biol
Year:		1986
Volume:		6
Issue:		6
Page Number:		2106 - 2114
DOI:		10.1128/mcb.6.6.2106-2114.1986
ISSN/ISBN:		0270-7306 (Print) 1098-5549 (Electronic) 0270-7306 (Linking)
Abstract:		"The Saccharomyces cerevisiae STE2 gene, which is required for pheromone response and conjugation specifically in mating-type a cells, was cloned by complementation of the ste2 mutation. Transcription of STE2 is repressed by the MAT alpha 2 gene product, so that the 1.4-kilobase STE2 RNA is detected only in a or mat alpha 2 strains, not in alpha or a/alpha cells. However, STE2 RNA levels are also increased by the mating pheromone alpha-factor and decreased in strains bearing mutations in the nonspecific STE4 gene. Regulation of STE2 expression in a cells is therefore achieved by several mechanisms"
Keywords:		"Base Sequence Conjugation, Genetic Gene Expression Regulation *Genes, Fungal *Genes, Mating Type, Fungal Genetic Complementation Test Mating Factor Peptides/physiology Pheromones/physiology Receptors, Cell Surface/*genetics Saccharomyces cerevisiae/*genet;"
Notes:		"MedlineHartig, A Holly, J Saari, G MacKay, V L eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. 1986/06/01 Mol Cell Biol. 1986 Jun; 6(6):2106-14. doi: 10.1128/mcb.6.6.2106-2114.1986"