| Title: | "Butane-2,3-dione: the key contributor to axillary and foot odor associated with an acidic note" |
| Author(s): | Hara T; Kyuka A; Shimizu H; |
| Address: | "Mandom Corporation, Technical Development Center, 5 - 12 Juniken-cho, Chuo-ku, Osaka 540-8530, Japan (phone: +81-6-67675024; fax: +81-6-67675047). hara-t@mandom.co.jp" |
| ISSN/ISBN: | 1612-1880 (Electronic) 1612-1872 (Linking) |
| Abstract: | "Human body odor, which contains several volatile organic compounds, possesses various odor qualities. To identify key volatile compounds responsible for the common unpleasant odors derived from human axillae and feet, the odor quality and intensity of 118 human axillae and feet were directly evaluated by sniffing, and odor compounds obtained from the subjects were identified. Furthermore, the sensory differences in odor intensity and quality with and without addition of butane-2,3-dione were evaluated by using the visual analog scale (VAS). An acidic odor was a common unpleasant note in human axillae and feet. Butane-2,3-dione was identified as a key compound associated with this odor. Strong positive correlations between the amount of butane-2,3-dione, and the odor intensities of axillae and feet were observed, and the addition of butane-2,3-dione solution to blended short-chain fatty-acid solutions caused significantly increased VAS values of axillary-like odor, unpleasantness, and odor intensity compared to those of each solution without added butane-2,3-dione" |
| Keywords: | "Axilla/physiology Butanones/analysis/*chemistry/isolation & purification Foot/physiology Gas Chromatography-Mass Spectrometry Humans Male *Odorants Skin/chemistry/metabolism Solid Phase Microextraction Axilary odor Butane-2, 3-dione Diacetyl Foot odor GC/M;" |
| Notes: | "MedlineHara, Takeshi Kyuka, Ayumi Shimizu, Hironori eng Switzerland 2015/02/14 Chem Biodivers. 2015 Feb; 12(2):248-58. doi: 10.1002/cbdv.201400272" |
