| Title: | Engineering resistance to virus transmission |
| Author(s): | Groen SC; Wamonje FO; Murphy AM; Carr JP; |
| Address: | "Department of Biology, Center for Genomics and Systems Biology, New York University, New York, NY 10003, USA. Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, UK. Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, UK. Electronic address: jpc1005@hermes.cam.ac.uk" |
| DOI: | 10.1016/j.coviro.2017.07.005 |
| ISSN/ISBN: | 1879-6265 (Electronic) 1879-6257 (Linking) |
| Abstract: | "Engineering plants for resistance to virus transmission by invertebrate vectors has lagged behind other forms of plant protection. Vectors typically transmit more than one virus. Thus, vector resistance could provide a wider range of protection than defenses directed solely against one virus or virus group. We discuss current knowledge of vector-host-virus interactions, the roles of viral gene products in host and vector manipulation, and the effects of semiochemicals on host-vector interactions, and how this knowledge could be employed to disrupt transmission dynamics. We also discuss how resistance to vectors could be generated through genetic engineering or gene editing or indirectly through use of biocontrol using plant-resident viruses that infect vectors" |
| Keywords: | "Animals *Disease Resistance Insect Vectors/*immunology/virology Plant Diseases/*immunology/*parasitology/virology Plants/*immunology/*parasitology/virology Plants, Genetically Modified/immunology/parasitology/virology;" |
| Notes: | "MedlineGroen, Simon C Wamonje, Francis O Murphy, Alex M Carr, John P eng BB/J011762/1/Biotechnology and Biological Sciences Research Council/United Kingdom BB/P023223/1/Biotechnology and Biological Sciences Research Council/United Kingdom Review Netherlands 2017/07/28 Curr Opin Virol. 2017 Oct; 26:20-27. doi: 10.1016/j.coviro.2017.07.005. Epub 2017 Jul 24" |
