| Title: | Gas chromatography with diode array detection in series with flame ionisation detection |
| Author(s): | Gras R; Luong J; Shellie RA; |
| Address: | "Dow Chemical Canada ULC, Highway 15, Fort Saskatchewan, Alberta, T8L 2P4, Canada; ARC Training Centre for Portable Analytical Separation Technologies (ASTech), University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia; Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia. ARC Training Centre for Portable Analytical Separation Technologies (ASTech), University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia; Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia; Trajan Scientific and Medical, 7 Argent Place Ringwood, Victoria 3154 Australia. Electronic address: rshellie@trajanscimed.com" |
| DOI: | 10.1016/j.chroma.2017.04.016 |
| ISSN/ISBN: | 1873-3778 (Electronic) 0021-9673 (Linking) |
| Abstract: | "We introduce a gas chromatography detection approach that uses diode array detection operated in series with flame ionisation detection and demonstrate the utility of the detection approach for determination of volatile organic compounds. Diode array detection brings ultraviolet - visible spectroscopy (over a range of 190-640nm) onto the capillary gas chromatography time-scale, where average peak widths of analytes are on the order of 3-5s. The non-destructive nature of the diode array detector affords serially-coupled flame ionisation detection. This arrangement delivers near-simultaneous selective and universal detection without incurring additional analytical time, and without recourse to column flow splitting. The hyphenated technique is shown to be effective for chromatographic applications spanning an equivalent volatility range from C(1) to C(7)n-paraffin hydrocarbons. The approach introduced herein provides increased sensitivity and selectivity for classes of compounds amenable to electronic spectroscopy such as alkenes, dienes, sulfurs, and aromatic compounds. The approach is demonstrated for direct measurement of carbon disulfide in work place atmospheres with a detection limit of 93pg on column and for the direct measurement of 1,3-butadiene in hydrocarbon matrices and ambient air with a detection of 73pg on column, each in less than 5min" |
| Keywords: | "Butadienes/analysis Chromatography, Gas/instrumentation/*methods Flame Ionization/instrumentation/*methods Hydrocarbons/analysis Limit of Detection Paraffin/analysis Volatile Organic Compounds/analysis Dad Diode array detection Gc-uv-fid Gas chromatograph;" |
| Notes: | "MedlineGras, Ronda Luong, Jim Shellie, Robert A eng Evaluation Study Netherlands 2017/04/27 J Chromatogr A. 2017 Jun 2; 1500:153-159. doi: 10.1016/j.chroma.2017.04.016. Epub 2017 Apr 12" |
