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Crit Rev Food Sci Nutr

Title:		"Bergamotenes: A comprehensive compile of their natural occurrence, biosynthesis, toxicity, therapeutic merits and agricultural applications"
Author(s):		Annaz H; El Fakhouri K; Ben Bakrim W; Mahdi I; El Bouhssini M; Sobeh M;
Address:		"AgroBioSciences Program, College for Sustainable Agriculture and Environmental Science, Mohammed VI Polytechnic University, Ben Guerir, Morocco. African Sustainable Agriculture Research Institute (ASARI), College for Sustainable Agriculture and Environmental Science, Mohammed VI Polytechnic University, Laayoune, Morocco"
Journal Title:		Crit Rev Food Sci Nutr
Year:		2023
Volume:		20230306
Issue:
Page Number:		1 - 20
DOI:		10.1080/10408398.2023.2184766
ISSN/ISBN:		1549-7852 (Electronic) 1040-8398 (Linking)
Abstract:		"Sesquiterpenoids constitute the largest subgroup of terpenoids that have numerous applications in pharmaceutical, flavor, and fragrance industries as well as biofuels. Bergamotenes, a type of bicyclic sesquiterpenes, are found in plants, insects, and fungi with alpha-trans-bergamotene as the most abundant compound. Bergamotenes and their related structures (Bergamotane sesquiterpenoids) have been shown to possess diverse biological activities such as antioxidant, anti-inflammatory, immunosuppressive, cytotoxic, antimicrobial, antidiabetic, and insecticidal effects. However, studies on their biotechnological potential are still limited. This review compiles the characteristics of bergamotenes and their related structures in terms of occurrence, biosynthesis pathways, and biological activities. It further discusses their functionalities and potential applications in pharmaceutical, nutraceuticals, cosmeceuticals, and pest management sectors. This review also opens novel perspectives in identifying and harnessing bergamotenes for pharmaceutical and agricultural purposes"
Keywords:		Bergamotenes biosynthesis occurrence pheromones alpha-trans-bergamotene;
Notes:		"PublisherAnnaz, Hassan El Fakhouri, Karim Ben Bakrim, Widad Mahdi, Ismail El Bouhssini, Mustapha Sobeh, Mansour eng 2023/03/07 Crit Rev Food Sci Nutr. 2023 Mar 6:1-20. doi: 10.1080/10408398.2023.2184766"